More recent studies of water samples taken near where methyl parathion was. Methyl parathion degrades rapidly in seawater, lake, and river waters, with 100% degradation occurring within 2 weeks to 1 month or more. Page 9 of 31 parathionmethyl specifications 2001 maximum. March 29, 2005 material safety data sheet section 1 product and company identification product identifier. Methyl parathion is hydrolyzed by, and therefore not compatible with, alkaline materials.
Page 9 of 31 parathion methyl specifications 2001 maximum. India veritas house, 70 mint road, fort, mumbai 400 001. These methyl parathion manufacturing companies are providing good quality products at low prices. Find here list of methyl parathion cas no 298000, methyl parathion manufacturers, methyl parathion suppliers and exporters. Cdc niosh pocket guide to chemical hazards methyl parathion. An initial decrease of 8 orders followed by 14 orders increase in adsorption is observed in moving from 10. Aerial application of parathion ec may only be done by a registered aerial application operator using a. The central nervous system, blood, respiratory system, eyes, and skin are the organs most affected by acute exposure of humans to. The commercial product is a tan liquid xylene solution with a pungent odor. The health concerns of the use of methyl parathion have resulted in cancellation of its use in most food crops in the united states. P202 do not handle until all safety precautions have been read and understood. Identification of the substancemixture and of the companyundertaking product name. Tolerances or maximum residue limits for ethyl parathion and its methyl homolog methyl parathion have been established for several commodities please see 40 cfr 180.
Methyl parathion is an acetylcholinesterase inhibitor, and excessive exposure can cause sweating, salivation, diarrhea, bradycardia, bronchoconstriction, muscle fasciculations, and coma. Methyl parathion is a pesticide that is used to kill insects on crops. Pakistan has banned the use of methylethyl parathions, but they are still illegally used. By the dermal route, methyl parathion is much less toxic than parathion, with an ld50 of 67 mgkg in rats of both sexes hayes 1963ex. Any insect population may contain individuals naturally resistant to parathion ec and any other group code 1b insecticide. It is structurally very similar to parathion ethyl. A different behavior is depicted by barren soil field samples for the removal of methyl parathion with change in concentration. Usually with the liquid solvent it is a combustible liquid.
Degradation is faster in the presence of sediments, and is faster in fresh water than in salt water. Paraoxon is one of the most potent acetylcholinesteraseinhibiting insecticides available, around 70% as potent as the nerve agent sarin, and so is now. Adsorption kinetics indicates that a good correlation exists between distribution coefficient kd and soil organic carbon. Iupac name o, o dimethyl o4nitrophenyl phosphorothioate 3. The technicalgrade methyl parathion smells like rotten eggs or garlic. Parathion methyl d6 dimethyld 6 pestanal, analytical standard synonym.
Sampling and analytical methods methyl parathion partially. O,odimethyld 6 o4nitrophenyl phosphorothioate, methyl parathion d 6. Parathion is a deep brown to yellow liquid with a faint odor of garlic. The pharmacokinetics and pharmacodynamics of methyl parathion are complex, and the complexity varies with the route of exposure. Methyl parathion penncapm cancellation request 1099. The resistant individuals can eventually dominate the insect population if these insecticides are used repeatedly. Parathion methyl, or methyl parathion, is an organophosphate insecticide, possessing an organothiophosphate group.
A chronicle of misuse and preventable human exposure. Pocket guide to chemical hazards material type value methyl parathion cas twa 0. Methyl parathion is an organophosphate op insecticide and acaricide, which is registered to control insect pests on food, feed and fiber crops. It was originally developed by ig farben in the 1940s. Methyl parathions acute oral ld50 for male rats is almost identical to that of parathion, i. Parathion 56382 hazard summary exposure may occur from the use of parathion as an insecticide on agricultural crops. These procedures were designed and tested for internal use by osha personnel. These tests are not usually available at your doctors office, but your doctor can send the samples to a laboratory that can perform the tests. It is an organophosphate oxon, and the active metabolite of the insecticide parathion. Material safety data sheet methyl acetate section 1 chemical product and company identification msds name. Material safety data sheet for methyl parathion, product number. A significant first pass effect for methyl parathion is seen with. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. It is highly toxic to nontarget organisms, including humans, so its use has been banned or restricted in most countries.
Note 2 the congelation temperature range should be nominated. Estimating solubility of parathion in organic solvents ilker polatoglu, y. However, exposure to methyl parathion may occur at farms where it has been used as a pesticide. Contact with skin, i nhalation of dust or spray, or swallowing may be fatal.
The general population is probably not exposed to methyl parathion. Parathion, also called parathion ethyl or diethyl parathion and locally known as folidol, is an organophosphate insecticide and acaricide. Vomiting, diarrhea, abdominal pain, seizures, and coma may also. It may be attributed to more available binding sites and less steric hindrance of methyl parathion. It is also used as an opthamological drug against glaucoma. It is not allowed for sale and import in nearly all countries around the world, while a few allow it under subject to specified conditions only. Buy high purity methyl parathion analytical standards from chem service inc. Australia are required to produce a material safety data sheet.
Op interim reregistration eligibility decisions ireds, therefore, are considered completed reds. The present study is an attempt to estimate the residual concentration and to suggest remedial solution of adsorption by different types of. Under certain exposure conditions, methyl parathion can affect the central nervous system resulting in dizziness, headache, difficulty breathing, vomiting, diarrhea, tremors, blurred vision, sweating. The first draft of methyl parathion in drinkingwater, background document for. Methyl parathion is a brownish liquid that turns milky. Physical and chemical properties of methyl parathion 23 s.
Methyl parathion represents the oldest generation of anticholinesterase insecticides that exhibit marked mammalian toxicity. Notice of receipt of a request to voluntarily amend methyl parathion pesticide registrations to terminate uses november 27, 2006 comment period closed on december 22, 2006 june 2, 2004 comment period closed on august 2, 2004. Common name methyl parathion, parathion methyl, metaphos 4. Methyl parathion is not meant to be used inside buildings or homes. Methyl parathion in drinkingwater world health organization. O,odimethyld 6 o4nitrophenyl phosphorothioate, methyl parathion d 6 empirical formula hill notation. Methyl parathion is a white crystalline solid which is often dissolved in a liquid solvent carrier. Methyl parathion is an organophosphorus op insecticide with insecticidal properties derived from acetylcholinesterase ache inhibition. Parathion is extremely toxic from acute shortterm inhalation, oral, and dermal exposures. Sample 14 c expressed as mg parathionmethyl per kg of tissue or eggs mean of 5 hens liver 0. Methyl parathion is a brownish liquid that turns milky white. It is a category i toxicant, and thus, is classified as a restricteduse.
Parathion ec material safety data sheet villa crop. Methyl parathion 4 ec page 4 of 7 msds revision date ddmmyyyy. The photocatalytic degradation of o,odimethyl opnitrophenyl phosphorothioate common name methyl parathion in aqueous tio 2 suspensions is reported in this study. Signs and symptoms of acute parathion methyl exposure. Poisoning with methyl parathion leads to cholinergic overstimulation with signs of toxicity including sweating, dizziness, vomiting, diarrhea. A wide variety of methyl parathion options are available to you, there are 9 suppliers who sells methyl parathion on, mainly located in asia. People who live close to areas of methyl parathion use also may be exposed to larger amounts of methyl parathion, because small amounts of the pesticide will move from the place where it is used to nearby areas. Methyl parathion definition is a highly toxic synthetic organophosphate insecticide c8h10no5ps.
October 27, 1999 volume 64, number 207 notices page 5787757881 from the federal register online via gpo access wais. It is toxic by inhalation, ingestion and skin absorption. Chemodynamics of methyl parathion and ethyl parathion. Methyl parathion is often detected in foods and air samples collected where methyl parathion is used. Methyl parathion 4 ec page 3 of 7 msds revision date ddmmyyyy.
O,odimethyld 6 o4nitrophenyl phosphorothioate, methyl parathiond 6 empirical formula hill notation. Mention of any company name or commercial product does not constitute endorsement by osha. Methyl parathion should not be heated above 55 degrees c. The top countries of supplier is china, from which the percentage of methyl parathion supply is 100% respectively. Most commonly, it is used on cotton, soybean and vegetable fields.
Frl63878 methyl parathion, receipt of requests for cancellation. This product can kill you if swallowed even in small amounts. Parathion, also called parathionethyl or diethyl parathion and locally clarification needed known as folidol, is an organophosphate insecticide and acaricide. It is an organic phosphate insecticide which acts as an inhibitor of cholinesterase, and as such it is highly toxic by all routes of exposure. Methyl parathion penncapm cancellation request 1099 federal register. It decomposes rapidly above 100 degrees c, creating an explosion hazard.
The results are graphically presented in figures figures1 1 and and2 2. Methyl parathion detection in vegetables and fruits using. Methyl parathion is removed more efficiently by seven orders of magnitude than ethyl parathion. Source of sample, shell oil company, shell chemical division. Methyl parathion synonyms, methyl parathion antonyms. Methyl parathion contains 4 pounds of methyl parathion. The aim of this article is to identify the intermediate organic reaction products using a number of analytical techniques, such as uvvis, hplc, gcms and 1 h nmr. Methyl parathion manufacturers, methyl parathion suppliers. Methyl parathion coefficient of wateroil distribution. Acute exposure to parathion methyl may produce the following signs and symptoms. Empirical formula hill notation c 8 d 6 h 4 no 5 ps.
Reports of methyl parathion intoxication, usually seen only in field pesticide applicators, have increased throughout the united states as a result of unauthorized application of methyl parathion inside homes. The toxicity of organophosphate insecticides for nontarget organism has been the subject of extensive research for sustainable agriculture. Mar 03, 2011 however, low levels of cholinesterase may be a result of methyl parathion exposure or it could be caused by factors other than methyl parathion. Paraoxon is a synthetic aryl dialkyl phosphate compound and organophosphate acetylcholinesterase inhibitor that is the active metabolite of the insecticide parathion and is used as a pesticide.
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